The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

Nearly every extracellular ligand that has been found to play a role in regulating bone biology acts, at least in part, through MAPK pathways. Nevertheless, much remains to be learned about the contribution of MAPKs to osteoblast biology in vivo. Here we report that the p38 MAPK pathway is required...

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Autors principals: Greenblatt, Matthew B., Shim, Jae-Hyuck, Zou, Weiguo, Sitara, Despina, Schweitzer, Michelle, Hu, Dorothy, Lotinun, Sutada, Sano, Yasuyo, Baron, Roland, Park, Jin Mo, Arthur, Simon, Xie, Min, Schneider, Michael D., Zhai, Bo, Gygi, Steven, Davis, Roger, Glimcher, Laurie H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898605/
https://ncbi.nlm.nih.gov/pubmed/20551513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42285
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