Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice

Hepcidin is a peptide hormone that regulates iron homeostasis and acts as an antimicrobial peptide. It is expressed and secreted by a variety of cell types in response to iron loading and inflammation. Hepcidin mediates iron homeostasis by binding to the iron exporter ferroportin, inducing its inter...

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Autores principales: De Domenico, Ivana, Zhang, Tian Y., Koening, Curry L., Branch, Ryan W., London, Nyall, Lo, Eric, Daynes, Raymond A., Kushner, James P., Li, Dean, Ward, Diane M., Kaplan, Jerry
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898601/
https://ncbi.nlm.nih.gov/pubmed/20530874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42011
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