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Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates

HSC transplantation using genetically modified autologous cells is a promising therapeutic strategy for various genetic diseases, cancer, and HIV. However, for many of these conditions, the current efficiency of gene transfer to HSCs is not sufficient for clinical use. The ability to increase the pe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Beard, Brian C., Trobridge, Grant D., Ironside, Christina, McCune, Jeannine S., Adair, Jennifer E., Kiem, Hans-Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898586/
https://ncbi.nlm.nih.gov/pubmed/20551514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40767
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