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Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analyses
Ribonucleotide reductase (RNR) synthesizes deoxyribonucleotides for DNA replication and repair and is controlled by sophisticated allosteric regulation involving differential affinity of nucleotides for regulatory sites. We have developed a robust and sensitive method for coupling biotinylated RNRs...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898501/ https://ncbi.nlm.nih.gov/pubmed/20534631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq035 |
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