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Fab crystallization and preliminary X-ray analysis of NC-1, an anti-HIV-1 antibody that recognizes the six-helix bundle core of gp41

NC-1 is a murine monoclonal antibody that specifically recognizes the six-helix bundle core of the human immunodeficiency virus type 1 (HIV-1) gp41. As such, it is a useful tool for probing gp41 conformations in HIV-1 membrane fusion. To establish the structural basis underlying the NC-1 specificity...

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Detalhes bibliográficos
Main Authors: Jin, Lei, Pan, Chungen, Qi, Zhi, Zhou, Z. Hong, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898479/
https://ncbi.nlm.nih.gov/pubmed/20606291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110019287
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