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Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca(2+) Currents in Isolated Lysosomes

Two-pore channels (TPCNs) have been proposed to form lysosomal Ca(2+) release channels that are activated by nicotinic acid adenine dinucleotide phosphate. Here, we employ a glass chip-based method to record for the first time nicotinic acid adenine dinucleotide phosphate -dependent currents through...

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Detalhes bibliográficos
Main Authors: Schieder, Michael, Rötzer, Katrin, Brüggemann, Andrea, Biel, Martin, Wahl-Schott, Christian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898409/
https://ncbi.nlm.nih.gov/pubmed/20495006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.143123
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