A Single Residue Switch for Mg(2+)-dependent Inhibition Characterizes Plant Class II Diterpene Cyclases from Primary and Secondary Metabolism

Class II diterpene cyclases mediate the acid-initiated cycloisomerization reaction that serves as the committed step in biosynthesis of the large class of labdane-related diterpenoid natural products, which includes the important gibberellin plant hormones. Intriguingly, these enzymes are differenti...

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Bibliografiska uppgifter
Huvudupphovsmän: Mann, Francis M., Prisic, Sladjana, Davenport, Emily K., Determan, Mara K., Coates, Robert M., Peters, Reuben J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Enzymology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898348/
https://ncbi.nlm.nih.gov/pubmed/20430888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123307
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