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Catalytic bases and stereo-control in Lamiaceae class II diterpene cyclases

Plants from the widespread Lamiaceae family produce many labdane-related diterpenoids, a number of which serve medicinal roles, and whose biosynthesis is initiated by class II diterpene cyclases (DTCs). These enzymes utilize a general acid-base catalyzed cyclo-isomerization reaction to produce vario...

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Bibliografische gegevens
Gepubliceerd in:Biochemistry
Hoofdauteurs: Schulte, Samuel, Potter, Kevin C., Lemke, Cody, Peters, Reuben J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019628/
https://ncbi.nlm.nih.gov/pubmed/29787239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00193
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