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Murine Gammaherpesvirus 68 LANA Is Essential for Virus Reactivation from Splenocytes but Not Long-Term Carriage of Viral Genome

ORF73, which encodes the latency-associated nuclear antigen (LANA), is a conserved gamma-2-herpesvirus gene. The murine gammaherpesvirus 68 (MHV68) LANA (mLANA) is critical for efficient virus replication and the establishment of latent infection following intranasal inoculation. To test whether the...

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Detalhes bibliográficos
Main Authors: Paden, Clinton R., Forrest, J. Craig, Moorman, Nathaniel J., Speck, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898264/
https://ncbi.nlm.nih.gov/pubmed/20444892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00133-10
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