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APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis
The mammalian APOBEC3 proteins are an important component of the cellular innate immune response to retroviral infection. APOBEC3G can extinguish HIV-1 infectivity by its incorporation into virus particles and subsequent cytosine deaminase activity that attacks the nascent viral cDNA during reverse...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898230/ https://ncbi.nlm.nih.gov/pubmed/20463080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00056-10 |
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