Functional Analysis of the Influenza Virus H5N1 Nucleoprotein Tail Loop Reveals Amino Acids That Are Crucial for Oligomerization and Ribonucleoprotein Activities

Homo-oligomerization of the nucleoprotein (NP) of influenza A virus is crucial for providing a major structural framework for the assembly of viral ribonucleoprotein (RNP) particles. The nucleoprotein is also essential for transcription and replication during the virus life cycle. In the H5N1 NP str...

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Detalhes bibliográficos
Main Authors: Chan, Wai-Hon, Ng, Andy Ka-Leung, Robb, Nicole C., Lam, Mandy Ka-Han, Chan, Paul Kay-Sheung, Au, Shannon Wing-Ngor, Wang, Jia-Huai, Fodor, Ervin, Shaw, Pang-Chui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898228/
https://ncbi.nlm.nih.gov/pubmed/20463064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02474-09
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