Stabilization of Influenza Virus Replication Intermediates Is Dependent on the RNA-Binding but Not the Homo-Oligomerization Activity of the Viral Nucleoprotein

The influenza virus nucleoprotein (NP) is believed to play a central role in directing a switch from RNA genome transcription to replication by the viral RNA polymerase. However, this role has recently been disputed with the proposal of alternative regulatory mechanisms. It has been suggested that t...

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Bibliographic Details
Main Authors: Vreede, Frank T., Ng, Andy Ka-Leung, Shaw, Pang-Chui, Fodor, Ervin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209277/
https://ncbi.nlm.nih.gov/pubmed/21917965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-11
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