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Stabilization of Influenza Virus Replication Intermediates Is Dependent on the RNA-Binding but Not the Homo-Oligomerization Activity of the Viral Nucleoprotein

The influenza virus nucleoprotein (NP) is believed to play a central role in directing a switch from RNA genome transcription to replication by the viral RNA polymerase. However, this role has recently been disputed with the proposal of alternative regulatory mechanisms. It has been suggested that t...

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Autores principales: Vreede, Frank T., Ng, Andy Ka-Leung, Shaw, Pang-Chui, Fodor, Ervin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209277/
https://ncbi.nlm.nih.gov/pubmed/21917965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-11
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