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Pro-proliferative FoxM1 is a target of p53-mediated repression
The p53 tumor suppressor protein acts as a transcription factor to modulate cellular responses to a wide variety of stresses. In this study we show that p53 is required for the downregulation of FoxM1, an essential transcription factor that regulates many G2/M-specific genes and is overexpressed in...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898139/ https://ncbi.nlm.nih.gov/pubmed/19749794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.282 |
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