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Pro-proliferative FoxM1 is a target of p53-mediated repression

The p53 tumor suppressor protein acts as a transcription factor to modulate cellular responses to a wide variety of stresses. In this study we show that p53 is required for the downregulation of FoxM1, an essential transcription factor that regulates many G2/M-specific genes and is overexpressed in...

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Auteurs principaux: Barsotti, AM, Prives, C
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898139/
https://ncbi.nlm.nih.gov/pubmed/19749794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.282
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