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FoxM1 Is a General Target for Proteasome Inhibitors

Proteasome inhibitors are currently in the clinic or in clinical trials, but the mechanism of their anticancer activity is not completely understood. The oncogenic transcription factor FoxM1 is one of the most overexpressed genes in human tumors, while its expression is usually halted in normal non-...

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Autori principali: Bhat, Uppoor G., Halasi, Marianna, Gartel, Andrei L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721658/
https://ncbi.nlm.nih.gov/pubmed/19672316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006593
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