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ROS-inhibitory activity of YopE is required for full virulence of Yersinia in mice
YopE, a type III secreted effector of Yersinia, is a GTPase Activating Protein for Rac1 and RhoA whose catalytic activity is critical for virulence. We found that YopE also inhibited reactive oxygen species (ROS) production and inactivated Rac2. How YopE distinguishes among its targets and which spe...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897941/ https://ncbi.nlm.nih.gov/pubmed/20148901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01448.x |
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