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A natural ribozyme with 3′,5′ RNA ligase activity
Using electrophoresis, sequencing and enzymatic digestion, we show that the group I intron from the cyanobacterium Anabaena sp. PCC 7120 catalyzes phosphodiester bond formation using a triphosphate on the 5′-terminal nucleotide, much like protein polymerases and engineered ribozymes. In the process,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897744/ https://ncbi.nlm.nih.gov/pubmed/19125157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.136 |
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