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RNA-directed construction of structurally complex and active ligase ribozymes through recombination

RNA-directed recombination can be used to catalyze a disproportionation reaction among small RNA substrates to create new combinations of sequences. But the accommodation of secondary and tertiary structural constraints in the substrates by recombinase ribozymes has not been explored. Here, we show...

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Detalhes bibliográficos
Main Authors: HAYDEN, ERIC J., RILEY, CRAIG A., BURTON, AARON S., LEHMAN, NILES
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370854/
https://ncbi.nlm.nih.gov/pubmed/16177133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2125305
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