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Mechanisms of covalent self-assembly of the Azoarcus ribozyme from four fragment oligonucleotides

RNA oligomers of length 40–60 nt can self-assemble into covalent versions of the Azoarcus group I intron ribozyme. This process requires a series of recombination reactions in which the internal guide sequence of a nascent catalytic complex makes specific interactions with a complement triplet, CAU,...

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Detalhes bibliográficos
Main Authors: Draper, Will E., Hayden, Eric J., Lehman, Niles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241849/
https://ncbi.nlm.nih.gov/pubmed/18048415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1055
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