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The Prodomain of Ssy5 Protease Controls Receptor-Activated Proteolysis of Transcription Factor Stp1

Extracellular amino acids induce the yeast SPS sensor to endoproteolytically cleave transcription factors Stp1 and Stp2 in a process termed receptor-activated proteolysis (RAP). Ssy5, the activating endoprotease, is synthesized with a large N-terminal prodomain and a C-terminal chymotrypsin-like cat...

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Detalhes bibliográficos
Main Authors: Pfirrmann, Thorsten, Heessen, Stijn, Omnus, Deike J., Andréasson, Claes, Ljungdahl, Per O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897576/
https://ncbi.nlm.nih.gov/pubmed/20421414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00323-10
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