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Spatial and temporal regulation of the endoproteolytic activity of the SPS-sensor–controlled Ssy5 signaling protease

The Saccharomyces cerevisiae Ssy5 signaling protease is a core component of the plasma membrane (PM)–localized SPS (Ssy1-Ptr3-Ssy5) sensor. In response to extracellular amino acids, the SPS-sensor orchestrates the proteasomal degradation of the inhibitory Ssy5 prodomain. The unfettered catalytic (Ca...

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Foilsithe in:Mol Biol Cell
Main Authors: Martins, António, Ring, Andreas, Omnus, Deike J., Heessen, Stijn, Pfirrmann, Thorsten, Ljungdahl, Per O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761765/
https://ncbi.nlm.nih.gov/pubmed/31461372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-02-0096
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