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A phosphodegron controls nutrient-induced proteasomal activation of the signaling protease Ssy5

Regulated proteolysis serves as a mechanism to control cellular processes. The SPS (Ssy1-Ptr3-Ssy5) sensor in yeast responds to extracellular amino acids by endoproteolytically activating transcription factors Stp1 and Stp2 (Stp1/2). The processing endoprotease Ssy5 is regulated via proteasomal degr...

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Autors principals: Omnus, Deike J., Pfirrmann, Thorsten, Andréasson, Claes, Ljungdahl, Per O.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145550/
https://ncbi.nlm.nih.gov/pubmed/21653827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0282
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