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Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell Adhesion

Rap1GAP expression is decreased in human tumors. The significance of its downregulation is unknown. We show that Rap1GAP expression is decreased in primary colorectal carcinomas. To elucidate the advantages conferred on tumor cells by loss of Rap1GAP, Rap1GAP expression was silenced in human colon c...

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Detalhes bibliográficos
Main Authors: Tsygankova, Oxana M., Ma, Changqing, Tang, Waixing, Korch, Christopher, Feldman, Michael D., Lv, Yu, Brose, Marcia S., Meinkoth, Judy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897574/
https://ncbi.nlm.nih.gov/pubmed/20439492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01345-09
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