Assessing the Potential of an Induced-Mutation Strategy for Avermectin Overproducers

Mutant libraries of avermectin-producing Streptomyces avermitilis strains were constructed by different mutagenesis strategies. A metric was applied to assess the mutation spectrum by calculating the distribution of average phenotypic distance of each population. The results showed for the first tim...

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Main Authors: Gao, Hong, Liu, Mei, Zhuo, Ying, Zhou, Xianlong, Liu, Jintao, Chen, Difei, Zhang, Wenquan, Gou, Zhongxuan, Shang, Peng, Zhang, Lixin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Methods
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897423/
https://ncbi.nlm.nih.gov/pubmed/20453119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01682-09
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