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Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061

BACKGROUND: The ketoisovalerate reductase (EC 1.2.7.7 ) is required for the formation of beauvericin via the nonribosomal peptide synthetase biosynthetic pathway. It catalyzes the NADPH-specific reduction of ketoisovaleric acid to hydroxyisovalerate. However, little is known about the bioinformatics...

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Bibliographic Details
Main Authors: Zhang, Tao, Jia, XiaoPeng, Zhuo, Ying, Liu, Mei, Gao, Hong, Liu, JinTao, Zhang, Lixin
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478992/
https://ncbi.nlm.nih.gov/pubmed/22916830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-55
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