Pharmacokinetics of Darunavir at 900 Milligrams and Ritonavir at 100 Milligrams Once Daily when Coadministered with Efavirenz at 600 Milligrams Once Daily in Healthy Volunteers

Ritonavir-boosted darunavir with efavirenz may be considered a nucleoside-sparing regimen for treatment-naïve HIV-infected patients. However, the pharmacokinetics of this combination administered once daily have not been studied. We conducted a three-period interaction study with healthy volunteers....

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Bibliographic Details
Main Authors: Soon, Gaik H., Shen, Ping, Yong, Eu-Leong, Pham, Paul, Flexner, Charles, Lee, Lawrence
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897301/
https://ncbi.nlm.nih.gov/pubmed/20385850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01564-09
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