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Pharmacokinetics of Indinavir at 800, 600, and 400 Milligrams Administered with Ritonavir at 100 Milligrams and Efavirenz in Ethnic Chinese Patients Infected with Human Immunodeficiency Virus

We assessed the pharmacokinetics of three different doses of indinavir in five patients. All doses achieved trough concentrations above efficacy thresholds. Toxic trough concentrations were observed in all patients receiving 800 mg, in two patients receiving 600 mg, and in none receiving 400 mg. Ind...

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Detalhes bibliográficos
Main Authors: Lee, Lawrence S., Panchalingam, Anushia, Yap, Marline C., Paton, Nicholas I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525429/
https://ncbi.nlm.nih.gov/pubmed/15504888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4476-4478.2004
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