p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis

Acute exposure to ionizing radiation can cause lethal damage to the gastrointestinal (GI) tract, a condition called the GI syndrome. Whether the target cells mediating the GI syndrome are derived from the epithelium or endothelium, and whether the target cells die by apoptosis or other mechanisms, a...

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Auteurs principaux: Kirsch, David G., Santiago, Philip M., di Tomasso, Emmanuelle, Sullivan, Julie M., Hou, Wu-Shiun, Dayton, Talya, Jeffords, Laura B., Sodha, Pooja, Mercer, Kim, Cohen, Rhianna, Takeuchi, Osamu, Korsmeyer, Stanley J., Bronson, Roderick, Kim, Carla F., Haigis, Kevin M., Jain, Rakesh K., Jacks, Tyler
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897160/
https://ncbi.nlm.nih.gov/pubmed/20019247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166202
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