Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers

Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the rate-limiting step of nicotinamide adenine dinucleotide (NAD(+)) synthesis and is required for cell growth, survival, DNA replication and repair, and angiogenesis. Nampt expression increases gene expression which promotes cell survival and...

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Bibliografische gegevens
Hoofdauteurs: Shackelford, Rodney E, Bui, Marilyn M, Coppola, Domenico, Hakam, Ardeshir
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2010
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897104/
https://ncbi.nlm.nih.gov/pubmed/20606733
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