Correlation between Mcl-1 and pAKT protein expression in colorectal cancer

Mcl-1 inhibits apoptosis in well-differentiated cells by sequestering BAD, BID, and BAX and other apoptotic molecules. pAKT blocks apoptotsis by facilitating the interaction of BAD with BCL-XL. Expression of pAKT and Mcl-1 have been described in colon cancer, however, the relationship between pAKT a...

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Bibliographic Details
Main Authors: Henderson-Jackson, Evita B, Helm, James, Ghayouri, Masoumeh, Hakam, Ardeshir, Nasir, Aejaz, Leon, Marino, Bui, Marilyn, Yeatman, Timothy, Coppola, Domenico
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993227/
https://ncbi.nlm.nih.gov/pubmed/21151390
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