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Increased Nicotinamide Phosphoribosyltransferase and Cystathionine-β-Synthase in Renal Oncocytomas, Renal Urothelial Carcinoma, and Renal Clear Cell Carcinoma

BACKGROUND: Renal oncocytomas (ROs), and clear cell (RCC) and urothelial carcinomas (UC), are common renal neoplasms. Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the rate-limiting step of NAD(+) synthesis and its expression is increased in several tumors. Nampt concomitantly regulates h...

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Detalhes bibliográficos
Publicado no:Anticancer Res
Main Authors: SHACKELFORD, RODNEY E., ABDULSATTAR, JEHAN, WEI, ERIC X., COTELINGAM, JAMES, COPPOLA, DOMENICO, HERRERA, GUILLERMO A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771350/
https://ncbi.nlm.nih.gov/pubmed/28668830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/anticanres.11709
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