Llwytho...

Synthesis and Preliminary Biological Studies of 3-Substituted Indoles Accessed by a Palladium-Catalyzed Enantioselective Alkene Difunctionalization Reaction

A unique alkene difunctionalization reaction has been developed which allows rapid construction of molecular complexity around the biologically relevant indole framework. The reaction proceeds with up to 87% yield, 99:1 er and >20:1 dr. Evaluation of several of the compounds reveals promising ant...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pathak, Tejas P., Gligorich, Keith M., Welm, Bryan E., Sigman, Matthew S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896870/
https://ncbi.nlm.nih.gov/pubmed/20486685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103472a
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