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Five- and Six-Coordinate Adducts of Nitrosamines with Ferric Porphyrins: Structural Models for the Type II Interactions of Nitrosamines with Ferric Cytochrome P450

Nitrosamines are well known for their toxic and carcinogenic properties. The metabolic activation of nitrosamines occur via interaction with the heme-containing cytochrome P450 enzymes. We report the preparation and structural characterization of a number of nitrosamine adducts of synthetic iron por...

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Xehetasun bibliografikoak
Egile Nagusiak: Xu, Nan, Goodrich, Lauren E., Lehnert, Nicolai, Powell, Douglas R., Richter-Addo, George B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896561/
https://ncbi.nlm.nih.gov/pubmed/20392126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic901751z
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