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Five- and Six-Coordinate Adducts of Nitrosamines with Ferric Porphyrins: Structural Models for the Type II Interactions of Nitrosamines with Ferric Cytochrome P450
Nitrosamines are well known for their toxic and carcinogenic properties. The metabolic activation of nitrosamines occur via interaction with the heme-containing cytochrome P450 enzymes. We report the preparation and structural characterization of a number of nitrosamine adducts of synthetic iron por...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896561/ https://ncbi.nlm.nih.gov/pubmed/20392126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic901751z |
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