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Efavirenz Binding to HIV-1 Reverse Transcriptase Monomers and Dimers
Efavirenz (EFV) is a nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 reverse transcriptase (RT) used for the treatment of AIDS. RT is a heterodimer composed of p66 and p51 subunits; p51 is produced from p66 by C-terminal truncation by HIV protease. The monomers can form p66/p66 and p5...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896556/ https://ncbi.nlm.nih.gov/pubmed/20039714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901579y |
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