Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress

Numerous human pathologies result from unrepaired oxidative DNA damage. Base excision repair (BER) is responsible for the repair of oxidative DNA damage that occurs in both nuclei and mitochondria. Despite the importance of BER in maintaining genomic stability, knowledge concerning the regulation of...

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Autores principales: Swartzlander, Dan B., Griffiths, Lyra M., Lee, Joan, Degtyareva, Natalya P., Doetsch, Paul W., Corbett, Anita H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896512/
https://ncbi.nlm.nih.gov/pubmed/20194111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq108
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