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Coordinating DNA replication by means of priming loop and differential synthesis rate
Genomic DNA is replicated by two DNA polymerase molecules: one works in close association with the helicase to copy the leading-strand template in a continuous manner while the second copies the already unwound lagging-strand template in a discontinuous manner through synthesis of Okazaki fragments1...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896039/ https://ncbi.nlm.nih.gov/pubmed/19924126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08611 |
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