DNA β-Amyloid(1–42) Trimer Immunization for Alzheimer Disease in a Wild-Type Mouse Model

CONTEXT: DNA β-amyloid(1–42) (Aβ42) trimer immunization was developed to produce specific T helper 2 cell (T(H)2)–type antibodies to provide an effective and safe therapy for Alzheimer disease (AD) by reducing elevated levels of Aβ42 peptide that occur in the brain of patients with AD. OBJECTIVE: To...

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Main Authors: Lambracht-Washington, Doris, Qu, Bao-Xi, Fu, Min, Eagar, Todd N., Stüve, Olaf, Rosenberg, Roger N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896011/
https://ncbi.nlm.nih.gov/pubmed/19861672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2009.1547
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