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Analysis of three plasmid systems for use in DNA Aβ42 immunization as therapy for Alzheimer’s Disease
In an effort to optimize DNA immunization-elicited antibody production responses against Aβ1-42 (Aβ42) as a therapy for Alzheimer’s disease (AD), comparisons were made between three distinct plasmid systems using gene-gun delivery. Plasmids encoding Aβ42 monomer and a novel Aβ42 trimeric fusion prot...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926979/ https://ncbi.nlm.nih.gov/pubmed/20562015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.05.054 |
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