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Changes in the brain transcriptome after DNA Aβ42 trimer immunization in a 3xTg-AD mouse model
Alzheimer’s disease (AD) has been associated with accumulation of amyloid beta (Aβ) peptides in brain, and immunotherapy targeting Aβ provides potential for AD prevention. We have used a DNA Aβ42 trimer construct for immunization of 3xTg-AD mice and found previously significant reduction of amyloid...
Tallennettuna:
| Julkaisussa: | Neurobiol Dis |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845550/ https://ncbi.nlm.nih.gov/pubmed/33316368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105221 |
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