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Contrasting Disease and Nondisease Protein Aggregation by Molecular Simulation

Protein aggregation can be defined as the sacrifice of stabilizing intrachain contacts of the functional state that are replaced with interchain contacts to form non-functional states. The resulting aggregate morphologies range from amorphous structures without long-range order typical of nondisease...

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Bibliografiska uppgifter
Huvudupphovsmän: Fawzi, Nicolas Lux, Yap, Eng-Hui, Okabe, Yuka, Kohlstedt, Kevin L., Brown, Scott P., Head-Gordon, Teresa
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895938/
https://ncbi.nlm.nih.gov/pubmed/18646868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar800062k
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