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Novel Expression Patterns of PI3K/AKT/mTOR Signaling Pathway Components in Colorectal Cancer
BACKGROUND: The PI3K/Akt/mTOR pathway plays a critical role in the growth and progression of colorectal cancer (CRC). The purpose of our study was twofold: 1) to determine the expression levels of several key components of this pathway including p85α, Akt1, Akt2, p-mTOR(Ser2448) and p-p70S6K(Thr389)...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895913/ https://ncbi.nlm.nih.gov/pubmed/20421047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2009.12.008 |
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