Novel Expression Patterns of PI3K/AKT/mTOR Signaling Pathway Components in Colorectal Cancer

BACKGROUND: The PI3K/Akt/mTOR pathway plays a critical role in the growth and progression of colorectal cancer (CRC). The purpose of our study was twofold: 1) to determine the expression levels of several key components of this pathway including p85α, Akt1, Akt2, p-mTOR(Ser2448) and p-p70S6K(Thr389)...

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Detaylı Bibliyografya
Asıl Yazarlar: Johnson, Sara M, Gulhati, Pat, Rampy, Bill A, Han, Yimei, Rychahou, Piotr G, Doan, Hung Q, Weiss, Heidi L, Evers, B Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895913/
https://ncbi.nlm.nih.gov/pubmed/20421047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2009.12.008
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