Bid Regulates the Pathogenesis of Neurotropic Reovirus

Reovirus infection leads to apoptosis in both cultured cells and the murine central nervous system (CNS). NF-κB-driven transcription of proapoptotic cellular genes is required for the effector phase of the apoptotic response. Although both extrinsic death-receptor signaling pathways and intrinsic pa...

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Bibliografiske detaljer
Main Authors: Danthi, Pranav, Pruijssers, Andrea J., Berger, Angela K., Holm, Geoffrey H., Zinkel, Sandra S., Dermody, Terence S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895667/
https://ncbi.nlm.nih.gov/pubmed/20617182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000980
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