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Reovirus Apoptosis and Virulence Are Regulated by Host Cell Membrane Penetration Efficiency

Apoptosis plays an important role in the pathogenesis of reovirus encephalitis and myocarditis in infected animals. Differences in apoptosis efficiency displayed by reovirus strains are linked to the viral μ1-encoding M2 gene segment. Studies using pharmacologic inhibitors of reovirus replication de...

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Detalhes bibliográficos
Main Authors: Danthi, Pranav, Kobayashi, Takeshi, Holm, Geoffrey H., Hansberger, Mark W., Abel, Ty W., Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224352/
https://ncbi.nlm.nih.gov/pubmed/17959662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01739-07
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