Reovirus Apoptosis and Virulence Are Regulated by Host Cell Membrane Penetration Efficiency

Apoptosis plays an important role in the pathogenesis of reovirus encephalitis and myocarditis in infected animals. Differences in apoptosis efficiency displayed by reovirus strains are linked to the viral μ1-encoding M2 gene segment. Studies using pharmacologic inhibitors of reovirus replication de...

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Autors principals: Danthi, Pranav, Kobayashi, Takeshi, Holm, Geoffrey H., Hansberger, Mark W., Abel, Ty W., Dermody, Terence S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224352/
https://ncbi.nlm.nih.gov/pubmed/17959662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01739-07
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