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Independent Regulation of Reovirus Membrane Penetration and Apoptosis by the μ1 ϕ Domain

Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein μ1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection. Ectopic expression of full-length and truncated f...

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Detalhes bibliográficos
Main Authors: Danthi, Pranav, Coffey, Caroline M., Parker, John S. L., Abel, Ty W., Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600812/
https://ncbi.nlm.nih.gov/pubmed/19112493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000248
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