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Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila

DNA double-strand breaks are repaired by multiple mechanisms that are roughly grouped into the categories of homology-directed repair and non-homologous end joining. End-joining repair can be further classified as either classical non-homologous end joining, which requires DNA ligase 4, or “alternat...

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Autori principali: Chan, Sze Ham, Yu, Amy Marie, McVey, Mitch
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895639/
https://ncbi.nlm.nih.gov/pubmed/20617203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001005
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