DIETARY FOLATE, ALCOHOL, AND B VITAMINS IN RELATION TO LINE-1 HYPOMETHYLATION IN COLON CANCER

BACKGROUND AND AIMS: Although critical for methylation reactions, how dietary folate and B vitamins affect global DNA methylation level in colon cancers is currently unknown. Long interspersed nucleotide element-1 (LINE-1) is an emerging indicator of genome-wide DNA methylation level that has previo...

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Detalhes bibliográficos
Main Authors: Schernhammer, E S, Giovannuccci, E, Kawasaki, T, Rosner, B, Fuchs, C S, Ogino, S
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895465/
https://ncbi.nlm.nih.gov/pubmed/19828464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2009.183707
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