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A Prospective Study of Dieatry Folate and Vitamin B and Colon Cancer According to MSI and KRAS Mutational Status
Sporadic microsatellite instability-high (MSI-high) colon cancers are positively associated with MLH1 promoter methylation, and inversely with KRAS mutation. One-carbon metabolism is critical for methylation reactions and nucleotide biosynthesis, but the influence of dietary one-carbon nutrients suc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741404/ https://ncbi.nlm.nih.gov/pubmed/18843035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0638 |
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